The Drug Assay Core is utilized for preclinical and clinical research studies that require the quantification of parent drug and metabolite concentrations in human plasma and urine samples. The analytical facility is well-equipped with a variety of instruments that include:

• HPLC systems with flourescence, UV-visible, radiochemical, electrochemical and photodiode array detection capabilities
• UV-visible spectrophotometer
• GC mass spectrometer
• GLC with chiral/nonchiral columns and nitrogen- phosphorous detection
• Beta and gamma scintillation counters
• Refrigerated high-speed and ultra-centrifuges

Drug Assay Core personnel have expertise in the design of preclinical and clinical pharmacology studies, and in the modeling of pharmacodynamic and pharmacokinetic systems.

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